ISDA: 22OW

Deposition Date 2026-01-19

Release Date 2026-07-08

Last Version Date 2026-07-08

Entry Detail

PDB ID:

22OW

Keywords:

TRANSFERASE

Title:

Crystal structure of O-adenosylmethionine-dependent methyltransferase McbD in complex with SAH

Biological Source:

Source Organism(s):

Marinactinospora thermotolerans (Taxon ID: 531310)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

3.00 Å

R-Value Free:

0.27

R-Value Work:

0.19

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Methyltransferase
Chain IDs:A, B
Chain Length:461
Number of Molecules:2
Biological Source:Marinactinospora thermotolerans

UniProt ID:A0A1V0EL88

Ligand Molecules

SAH

Primary Citation

Structural and Mechanistic Insights into the O ‐Methyltransferase McbD in Marinacarboline Biosynthesis.

Qiao, Z, Yang, X, Liu, J, Liu, L, Meng, X, He, X, Liu, G, Teng, Y.B, Chen, Q.Show

Acs Omega 11 34350 34356 (2026)

PMID: 42326699 DOI: 10.1021/acsomega.6c02087

Primary Citation of related structures

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