22IB image
Deposition Date 2026-01-12
Release Date 2026-04-22
Last Version Date 2026-04-22
Entry Detail
PDB ID:
22IB
Keywords:
STRUCTURAL PROTEIN
Title:
CryoEM structure of Human LonP1-TFAM complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.22 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
22IB validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Lon protease homolog, mitocho
Gene (Uniprot):LONP1
Chain IDs:A, B, C, D, E, F
Chain Length:585
Number of Molecules:6
Biological Source:Homo sapiens
UniProt ID:P36776 Pfam ID:PF00004, PF22667, PF05362 EC:3.4.21.53
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:TFAM substrate
Chain IDs:G
Chain Length:28
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:22IB
Ligand Molecules
ADP
AGS
MG
Primary Citation
Structural Analysis of Human LonP1 Protease Bound with the Native Substrate.
Life 16 ? ? (2026)
PMID: 41900996 DOI: 10.3390/life16030478
Primary Citation of related structures
22IB
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