ISDA: 22GM

Deposition Date 2026-01-09

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

22GM

Keywords:

MEMBRANE PROTEIN/IMMUNE SYSTEM

Title:

C5a bound C5aR1 in complex with beta-arrestin1

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Bos taurus (Taxon ID: 9913)

Expression System(s):

Escherichia coli, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-arrestin-1
Gene (Uniprot):ARRB1
Chain IDs:E (auth: A)
Chain Length:347
Number of Molecules:1
Biological Source:Bos taurus

UniProt ID:P17870 Pfam ID:PF00339, PF02752

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:C5a anaphylatoxin
Gene (Uniprot):C5
Chain IDs:A (auth: C)
Chain Length:74
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01031 Pfam ID:PF01821 EC:3.4.21.43

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fab30 heavy chain
Chain IDs:C (auth: H)
Chain Length:193
Number of Molecules:1
Biological Source:Mus musculus

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fab30 light chain
Chain IDs:D (auth: L)
Chain Length:164
Number of Molecules:1
Biological Source:Homo sapiens

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:C5a anaphylatoxin chemotactic
Gene (Uniprot):C5AR1, AVPR2
Chain IDs:B (auth: R)
Chain Length:371
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P21730,P30518 Pfam ID:PF00001

Modified Residue