ISDA: 22CR

Deposition Date 2026-01-06

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

22CR

Keywords:

MEMBRANE PROTEIN/IMMUNE SYSTEM

Title:

C5a-desArg bound C5aR2 in complex with beta-arrestin1

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)
Bos taurus (Taxon ID: 9913)

Expression System(s):

Escherichia coli, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.90 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Beta-arrestin-1
Gene (Uniprot):ARRB1
Mutagens:R169E
Chain IDs:E (auth: A)
Chain Length:393
Number of Molecules:1
Biological Source:Bos taurus

UniProt ID:P17870 Pfam ID:PF00339, PF02752

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:C5a anaphylatoxin
Gene (Uniprot):C5
Mutagens:C27R
Chain IDs:A (auth: C)
Chain Length:74
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P01031 Pfam ID:PF01821 EC:3.4.21.43

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fab30 heavy chain
Chain IDs:C (auth: H)
Chain Length:229
Number of Molecules:1
Biological Source:Mus musculus

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Fab30 light chain
Chain IDs:D (auth: L)
Chain Length:215
Number of Molecules:1
Biological Source:Mus musculus

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:C5a anaphylatoxin chemotactic
Gene (Uniprot):C5AR2
Chain IDs:B (auth: R)
Chain Length:337
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9P296 Pfam ID:PF00001

Modified Residue