ISDA: 21WC

Deposition Date 2025-12-31

Release Date 2026-05-13

Last Version Date 2026-05-13

Entry Detail

PDB ID:

21WC

Keywords:

NUCLEAR PROTEIN/DNA

Title:

Cryo-EM structure of the ATPase domain of SMARCA4 and the finger helix of BCL7A bound to a nucleosome

Biological Source:

Source Organism(s):

Xenopus laevis (Taxon ID: 8355)
Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3
Gene (Uniprot):LOC121398065
Chain IDs:A, E
Chain Length:135
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A310TTQ1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Chain IDs:B, F
Chain Length:102
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:P62799

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A
Gene (Uniprot):LOC494591
Chain IDs:C, G
Chain Length:129
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:Q6AZJ8

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B
Gene (Uniprot):LOC108704303
Chain IDs:D, H
Chain Length:125
Number of Molecules:2
Biological Source:Xenopus laevis

UniProt ID:A0A8J0U496

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:SMARCA4 isoform 2
Gene (Uniprot):SMARCA4
Chain IDs:I
Chain Length:1711
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9HBD4

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:B-cell CLL/lymphoma 7 protein
Gene (Uniprot):BCL7A
Chain IDs:J (auth: N)
Chain Length:216
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q4VC05

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (167-MER)
Chain IDs:K (auth: X)
Chain Length:167
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polydeoxyribonucleotide
Molecule:DNA (167-MER)
Chain IDs:L (auth: Y)
Chain Length:167
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules