ISDA: 21TY

Deposition Date 2025-12-26

Release Date 2026-09-09

Last Version Date 2026-09-09

Entry Detail

PDB ID:

21TY

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of Free fatty acid receptor 2 (FFA2)-ARK1 with GLPG0974

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.93 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Free fatty acid receptor 2,hu
Gene (Uniprot):FFAR2
Chain IDs:A
Chain Length:748
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:O15552 Pfam ID:PF00001

Ligand Molecules

A1LYD

Primary Citation

Universal pipeline for high-resolution GPCR structure determination.

Kojima, A, Kawakami, K, Kobayashi, N, Kobayashi, K, Matsui, T.E, Uemoto, K, Gu, Y, Narita, T.J, Kugawa, M, Fukuda, M, Kato, H.E.Show

Nat.Struct.Mol.Biol. ? ? ? (2026)

PMID: 42665663 DOI: 10.1038/s41594-026-01869-6

Primary Citation of related structures

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