ISDA: 21TT

Deposition Date 2025-12-24

Release Date 2026-10-14

Last Version Date 2026-10-14

Entry Detail

PDB ID:

21TT

Keywords:

TRANSFERASE

Title:

Prenylated FMN synthase from Methanosarcina mazei (MmPFS) in complex with prFMN in the radical form

Biological Source:

Source Organism(s):

Methanosarcina mazei (Taxon ID: 2209)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.72 Å

R-Value Free:

0.20

R-Value Work:

0.18

Space Group:

C 1 2 1

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Flavin prenyltransferase UbiX
Gene (Uniprot):vdcB
Chain IDs:A (auth: G), B (auth: H), C (auth: J), D (auth: A), E (auth: B), F (auth: C), G (auth: D), H (auth: E), I (auth: F), J (auth: I), K, L, M, N, O, P, Q, R
Chain Length:214
Number of Molecules:18
Biological Source:Methanosarcina mazei

UniProt ID:Q8PVT9 EC:2.5.1.129

Ligand Molecules

4LU

SO4

Primary Citation

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity.

Fukuhara, S, Unno, H, Ishimine, S, Nagata, R, Ito, T, Hemmi, H.Show

Febs J. ? ? ? (2026)

PMID: 42592911 DOI: 10.1111/febs.70694

Primary Citation of related structures

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