ISDA: 21TL

Deposition Date 2025-12-23

Release Date 2026-10-07

Last Version Date 2026-10-21

Entry Detail

PDB ID:

21TL

Keywords:

TRANSFERASE

Title:

Enterovirus 71 Polymerase Elongation Complex with a remdesivir nucleotide at product strand positions +1 (C1S5 form)

Biological Source:

Source Organism(s):

Enterovirus A71 (Taxon ID: 39054)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.70 Å

R-Value Free:

0.24

R-Value Work:

0.21

R-Value Observed:

0.21

Space Group:

P 65 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Enterovirus 71 polymerase
Chain IDs:A
Chain Length:468
Number of Molecules:1
Biological Source:Enterovirus A71

UniProt ID:Q5DW46 EC:3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48

Polymer Type:polyribonucleotide
Molecule:RNA (33-MER)
Chain IDs:C (auth: B)
Chain Length:33
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(*UP*GP*UP*UP*CP*GP*
Chain IDs:B (auth: C)
Chain Length:15
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules