21FG image
Deposition Date 2025-12-11
Release Date 2026-04-01
Last Version Date 2026-04-01
Entry Detail
PDB ID:
21FG
Keywords:
TRANSPORT PROTEIN
Title:
Cryo-EM structure of the human P2X3 receptor in the ATP- and sivopixant-bound closed state
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.34 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
21FG validation report
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:P2X purinoceptor 3
Gene (Uniprot):P2RX3
Chain IDs:A, B, C
Chain Length:327
Number of Molecules:3
Biological Source:Homo sapiens
UniProt ID:P56373 Pfam ID:PF00864
Ligand Molecules
A1E2N
ATP
NAG
Primary Citation
Cryo-EM structure of the human P2X3 receptor in the ATP- and sivopixant-bound closed state
To Be Published ? ? ? (?)
Primary Citation of related structures
21FG
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