21EX image
Deposition Date 2025-12-10
Release Date 2026-09-09
Last Version Date 2026-09-09
Entry Detail
PDB ID:
21EX
Keywords:
IMMUNE SYSTEM
Title:
Wild tipe p53WT-HLA-A2
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.02 Å
R-Value Free:
0.18
R-Value Work:
0.15
R-Value Observed:
0.16
Space Group:
C 1 2 1
21EX validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:MHC class I antigen
Gene (Uniprot):HLA-A
Chain IDs:A
Chain Length:276
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8WLS4
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Gene (Uniprot):B2M
Chain IDs:B
Chain Length:100
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P61769 Pfam ID:PF07654
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cellular tumor antigen p53
Gene (Uniprot):TP53
Chain IDs:C
Chain Length:9
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P04637
Primary Citation
Structural basis for T-cell receptor recognition of p53 Y220D , a human cancer neoantigen.
Acta Crystallogr D Struct Biol ? ? ? (2026)
PMID: 42599692 DOI: 10.1107/S2059798326007564
Primary Citation of related structures
21EX
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