21AU image
Deposition Date 2025-12-05
Release Date 2026-04-29
Last Version Date 2026-04-29
Entry Detail
PDB ID:
21AU
Keywords:
VIRAL PROTEIN
Title:
Epitope and functional classification of human neutralizing antibodies against SFTSV Gn
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Severe fever with thrombocytopenia syndrome virus (Taxon ID: 1003835)
Expression System(s):
Cricetulus griseus, Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.69 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
21AU validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:BD70-4003 heavy chain
Chain IDs:A
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:21AU
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:BD70-4003 light chain
Chain IDs:B
Chain Length:107
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:21AU
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:BD70-4017 heavy chain
Chain IDs:C
Chain Length:125
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:21AU
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:BD70-4017 light chain
Chain IDs:D
Chain Length:110
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:21AU
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Envelopment polyprotein
Chain IDs:E (auth: H)
Chain Length:321
Number of Molecules:1
Biological Source:Severe fever with thrombocytopenia syndrome virus
UniProt ID:A0A7S9CEK0
Ligand Molecules
NA
Primary Citation
Human monoclonal antibodies that target the SFTSV glycoprotein Gn head from four neutralizing epitope groups.
Cell Rep 45 117248 117248 (2026)
PMID: 41955097 DOI: 10.1016/j.celrep.2026.117248
Primary Citation of related structures
21AU
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