21AD image
Deposition Date 2025-12-04
Release Date 2026-10-21
Last Version Date 2026-10-21
Entry Detail
PDB ID:
21AD
Title:
Crystal Structure of Helicobacter pylori Urease Accessory Protein UreE(1-148) and UreG in complex with GMPPNP and nickel.
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.85 Å
R-Value Free:
0.27
R-Value Work:
0.24
R-Value Observed:
0.24
Space Group:
P 1 21 1
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Urease accessory protein UreG
Gene (Uniprot):ureG
Chain IDs:A, B, E, F
Chain Length:202
Number of Molecules:4
Biological Source:Helicobacter pylori
Polymer Type:polypeptide(L)
Molecule:Urease accessory protein UreE
Gene (Uniprot):ureE
Chain IDs:C, D, G, H
Chain Length:148
Number of Molecules:4
Biological Source:Helicobacter pylori
Primary Citation
Structural insights into how metallochaperones UreE and UreG interact to deliver a toxic metal to urease.
Proc.Natl.Acad.Sci.USA 123 e2535662123 e2535662123 (2026)
PMID: 42691087 DOI: 10.1073/pnas.2535662123
Primary Citation of related structures
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