ISDA: 20XK

Deposition Date 2025-12-01

Release Date 2026-09-16

Last Version Date 2026-09-16

Entry Detail

PDB ID:

20XK

Keywords:

PEPTIDE BINDING PROTEIN

Title:

Crystal structure of H-2Db with C.parvum peptide

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)
Cryptosporidium parvum (Taxon ID: 5807)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.20 Å

R-Value Free:

0.27

R-Value Work:

0.22

Space Group:

C 1 2 1

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:H-2 class I histocompatibilit
Chain IDs:A
Chain Length:275
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Beta-2-microglobulin
Chain IDs:B
Chain Length:98
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:LYS-ALA-VAL-LYS-ASN-PRO-ALA-P
Chain IDs:C
Chain Length:9
Number of Molecules:1
Biological Source:Cryptosporidium parvum

Ligand Molecules

GOL

Primary Citation

Structural Basis for the Immunological Paradox of a High-Affinity Yet Non-Immunogenic MHC-I Epitope from Cryptosporidium parvum.

Fan, S, Wang, T, Ren, S, Peng, J, Li, L, Zhao, Y, Yang, J, Zhang, Y, Yan, Y, Wang, H, Wang, Y.Show

Biology (Basel) 15 ? ? (2026)

PMID: 42589148 DOI: 10.3390/biology15151281

Primary Citation of related structures

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