13BV image
Deposition Date 2026-04-28
Release Date 2026-05-13
Last Version Date 2026-05-13
Entry Detail
PDB ID:
13BV
Keywords:
IMMUNE SYSTEM
Title:
Cryo-EM structure of human PI3KC3-C1 complex
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.77 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
13BV validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Phosphoinositide 3-kinase reg
Gene (Uniprot):PIK3R4
Chain IDs:D (auth: A)
Chain Length:1358
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q99570 Pfam ID:PF00069, PF22956, PF00400
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 3-kinase
Gene (Uniprot):PIK3C3
Chain IDs:A (auth: B)
Chain Length:887
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q8NEB9 Pfam ID:PF00792, PF00613, PF00454 EC:2.7.1.137
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Beclin 1-associated autophagy
Gene (Uniprot):ATG14
Chain IDs:B (auth: C)
Chain Length:492
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q6ZNE5 Pfam ID:PF10186 EC:2.7.1.137
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Beclin-1
Gene (Uniprot):BECN1
Chain IDs:C (auth: D)
Chain Length:450
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q14457 Pfam ID:PF15285, PF17675, PF04111
Ligand Molecules
GDP
MG
MYR
Primary Citation
Cryo-EM reconstruction of PI3KC3-C2 in complex with Rubicon Middle Region of C terminus
To Be Published ? ? ? (?)
Primary Citation of related structures
13BV
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