ISDA: 12YU

Deposition Date 2026-04-22

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

12YU

Keywords:

TRANSCRIPTION

Title:

Crystal structure of the BPTF PHD finger-Bromodomain bound to H3R2X3K4me3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli bl21(de3)

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.50 Å

R-Value Free:

0.18

R-Value Work:

0.16

R-Value Observed:

0.16

Space Group:

P 21 21 21

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nucleosome-remodeling factor
Gene (Uniprot):BPTF
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q12830 Pfam ID:PF00628, PF00439

Polymer Type:polypeptide(L)
Molecule:H3R2X3K4me3
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

GOL

Primary Citation

Crystal structure of H3R2X3K4me3 bound BPTF

Shao, Z, Song, J.Show

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