12WW image
Deposition Date 2026-04-21
Release Date 2026-10-21
Last Version Date 2026-10-21
Entry Detail
PDB ID:
12WW
Keywords:
TRANSFERASE
Title:
FGFR3 Kinase Domain with Inhibitor 4-[4-[3-chloro-4-[(1S)-1-(5-fluoro-2-pyridinyl)-2-hydroxyethoxy]pyrazolo[5-a]pyridin-6-yl]-5-methyltriazol-1-yl]piperidine-1-carbonitrile
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Spodoptera frugiperda
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.04 Å
R-Value Free:
0.25
R-Value Work:
0.19
R-Value Observed:
0.19
Space Group:
P 1 21 1
12WW validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Fibroblast growth factor rece
Gene (Uniprot):FGFR3
Chain IDs:A
Chain Length:312
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:P22607 EC:2.7.10.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
PTR A TYR modified residue
Ligand Molecules
A1DC5
SO4
Primary Citation
FGFR3 Kinase Domain with Inhibitor 4-[4-[3-chloro-4-[(1S)-1-(5-fluoro-2-pyridinyl)-2-hydroxyethoxy]pyrazolo[5-a]pyridin-6-yl]-5-methyltriazol-1-yl]piperidine-1-carbonitrile
To Be Published ? ? ? (?)
Primary Citation of related structures
12WW
Feedback Form
Name
Email
Institute
Feedback