12VQ image
Deposition Date 2026-04-20
Release Date 2026-08-19
Last Version Date 2026-08-19
Entry Detail
PDB ID:
12VQ
Keywords:
IMMUNE SYSTEM
Title:
H103A Human Aconitate Decarboxylase 1 mutant, apo
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.42 Å
R-Value Free:
0.18
R-Value Work:
0.15
Space Group:
P 21 21 2
12VQ validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Cis-aconitate decarboxylase
Mutagens:H103A
Chain IDs:A, B
Chain Length:462
Number of Molecules:2
Biological Source:Homo sapiens
Ligand Molecules
ACT
CA
GOL
NA
PEG
Primary Citation
Robust structural, kinetic and biophysical characterization of wild-type human ACOD1, selected mutants and their interaction with citraconate
J Struct Biol X 14 100157 ? (2026)
DOI: 10.1016/j.yjsbx.2026.100157
Primary Citation of related structures
12VQ
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