12OZ image
Deposition Date 2026-04-14
Release Date 2026-05-13
Last Version Date 2026-05-13
Entry Detail
PDB ID:
12OZ
Keywords:
MEMBRANE PROTEIN
Title:
Single particle cryo-EM structure of human MTCH2 (hyperactive mutant F285N F286N)
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)
Expression System(s):
Spodoptera frugiperda, Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.30 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
12OZ validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Mitochondrial carrier homolog
Gene (Uniprot):UCP1, MTCH2
Mutagens:F285N,F286N,L199V,A200Y,T226A
Chain IDs:A
Chain Length:304
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9Y6C9,P25874
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:UCP1 Nanobody
Chain IDs:B
Chain Length:127
Number of Molecules:1
Biological Source:synthetic construct
UniProt ID:12OZ
Ligand Molecules
NA
Primary Citation
Structural evolution of the MTCH family of mitochondrial insertases
To Be Published ? ? ? (?)
Primary Citation of related structures
12OZ
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