ISDA: 12KX

Deposition Date 2026-04-10

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

12KX

Keywords:

VIRAL PROTEIN

Title:

Crystal structure of H5 hemagglutinin D190/H226 from the A/British_Columbia/PHL-2032/2024 (H5N1)

Biological Source:

Source Organism(s):

Influenza A virus (Taxon ID: 11320)

Expression System(s):

Spodoptera aff. frugiperda 1 bold-2017

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.62 Å

R-Value Free:

0.29

R-Value Work:

0.25

R-Value Observed:

0.25

Space Group:

P 21 21 21

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin HA1
Chain IDs:A (auth: I), C (auth: A), E (auth: C)
Chain Length:323
Number of Molecules:3
Biological Source:Influenza A virus

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin HA2
Gene (Uniprot):HA
Chain IDs:B (auth: J), D (auth: B), F (auth: D)
Chain Length:174
Number of Molecules:3
Biological Source:Influenza A virus

UniProt ID:A0A8E4IDS0

Ligand Molecules

NAG

Primary Citation

Structural and functional characterization of hemagglutinin E190D and Q226H minor variants in human H5N1 A/British_Columbia/PHL-2032/2024 in citation information

Lin, T.H, Zhu, X, Santos, J.S.J, Wang, S, Babarinde, S, Yu, W, McBride, R, Paulson, J.C, Hensley, S.E, Wilson, I.A.Show

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Primary Citation of related structures

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