ISDA: 12KL

Deposition Date 2026-04-09

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

12KL

Keywords:

PROTEIN FIBRIL

Title:

SSNMR Structure of Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Murid betaherpesvirus 1 (Taxon ID: 10366)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

SOLID-STATE NMR

Conformers Calculated:

200

Conformers Submitted:

Selection Criteria:

structures with the least restraint violations

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Receptor-interacting serine/t
Gene (Uniprot):RIPK3
Chain IDs:A, C, E, G
Chain Length:133
Number of Molecules:4
Biological Source:Homo sapiens

UniProt ID:Q9Y572 EC:2.7.10.2

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ribonucleoside-diphosphate re
Gene (Uniprot):M45
Chain IDs:B, D, F, H
Chain Length:92
Number of Molecules:4
Biological Source:Murid betaherpesvirus 1

UniProt ID:H2A2P4

Ligand Molecules

Primary Citation

Structural Studies of an Anti-necroptosis Viral:Human Functional Hetero-amyloid M45:RIPK3 using SSNMR

He, C, Varghese, N.R, Keeler, E.G, Pham, C.L.L, Xie, T, Williams, B, Tetter, S, Seaman, C, Wilde, K.L, Brown, S.H.J, Bouwer, J.C, Gambin, Y, Sierecki, E, Steain, M, Zhou, R, Sunde, M, McDermott, A.E.Show

To be published ? ? ? (?)

Primary Citation of related structures

Feedback Form