ISDA: 12IE

Deposition Date 2026-04-07

Release Date 2026-08-26

Last Version Date 2026-08-26

Entry Detail

PDB ID:

12IE

Keywords:

Immune System/Viral Protein

Title:

Cryo-EM structure of B/Lee/1940 hemagglutinin trimer in complex with three KL-BHA-4C2 Fab fragments

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)
Influenza B virus (B/Lee/1940) (Taxon ID: 518987)

Expression System(s):

Mus musculus, Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.61 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Chain IDs:B (auth: A), F (auth: C), G (auth: B)
Chain Length:522
Number of Molecules:3
Biological Source:Influenza B virus (B/Lee/1940)

Polymer Type:polypeptide(L)
Molecule:KL-BHA-4C2 heavy chain
Chain IDs:A (auth: H), H (auth: D), I (auth: M)
Chain Length:120
Number of Molecules:3
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:KL-BHA-4C2 light chain
Chain IDs:C (auth: L), D (auth: N), E
Chain Length:111
Number of Molecules:3
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Cryo-EM structure of B/Lee/1940 hemagglutinin trimer in complex with three KL-BHA-4C2 Fab fragments

Civljak, A, Bonnettaz, B, Bajic, G.Show

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Primary Citation of related structures

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