12ID image
Deposition Date 2026-04-07
Release Date 2026-08-26
Last Version Date 2026-09-16
Entry Detail
PDB ID:
12ID
Keywords:
Viral Protein/Immune System
Title:
Cryo-EM structure of B/Lee/1940 hemagglutinin trimer in complex with three KL-BHA-3F4 Fab fragments
Biological Source:
Source Organism(s):
Influenza B virus (B/Lee/1940) (Taxon ID: 518987)
Mus musculus (Taxon ID: 10090)
Expression System(s):
Spodoptera frugiperda, Mus musculus
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.40 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
12ID validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Hemagglutinin
Chain IDs:A, D (auth: B), E (auth: C)
Chain Length:522
Number of Molecules:3
Biological Source:Influenza B virus (B/Lee/1940)
UniProt ID:Q0PLR5
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:KL-BHA-3F4 heavy chain
Chain IDs:B (auth: M), F (auth: H), G (auth: D)
Chain Length:123
Number of Molecules:3
Biological Source:Mus musculus
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:KL-BHA-3F4 light chain
Chain IDs:C (auth: N), H (auth: E), I (auth: L)
Chain Length:107
Number of Molecules:3
Biological Source:Mus musculus
Ligand Molecules
NAG
Primary Citation
Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms.
J.Virol. ? e0080226 e0080226 (2026)
PMID: 42696304 DOI: 10.1128/jvi.00802-26
Primary Citation of related structures
12ID
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