12EM image
Deposition Date 2026-03-30
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
12EM
Keywords:
CARBOHYDRATE
Title:
Crystal structure of a B1,3-Glucosyltransferase (B3GLCT) reveals an unusual mode of substrate recognition by a two-domain GT-A fold glycosyltransferase
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens, Escherichia coli 'bl21-gold(de3)plyss ag'
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
2.07 Å
R-Value Free:
0.22
R-Value Work:
0.19
R-Value Observed:
0.20
Space Group:
P 63 2 2
12EM validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Beta-1,3-glucosyltransferase
Chain IDs:A
Chain Length:433
Number of Molecules:1
Biological Source:Homo sapiens
Polymer Type:polypeptide(L)
Molecule:Thrombospondin-1
Chain IDs:B
Chain Length:61
Number of Molecules:1
Biological Source:Homo sapiens
Ligand Molecules
EDO
FUC
GOL
MN
NAG
UDP
Primary Citation
Crystal structure of a beta 1,3-Glucosyltransferase reveals an unusual substrate recognition by a two-domain GT-A fold glycosyltransferase.
J.Biol.Chem. ? 113418 113418 (2026)
PMID: 42575440 DOI: 10.1016/j.jbc.2026.113418
Primary Citation of related structures
12EM
Feedback Form
Name
Email
Institute
Feedback