11WZ image
Deposition Date 2026-03-16
Release Date 2026-09-02
Last Version Date 2026-09-02
Entry Detail
PDB ID:
11WZ
Keywords:
VIRAL PROTEIN/DNA
Title:
MPXV polymerase-E5 primase core complex
Biological Source:
Source Organism(s):
Monkeypox virus (Taxon ID: 10244)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.80 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
11WZ validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:DNA polymerase
Chain IDs:A
Chain Length:1006
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:Uracil-DNA glycosylase
Chain IDs:B
Chain Length:218
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:DNA polymerase processivity f
Chain IDs:F (auth: C)
Chain Length:426
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polypeptide(L)
Molecule:Uncoating factor OPG117
Chain IDs:D (auth: E), E (auth: D)
Chain Length:785
Number of Molecules:2
Biological Source:Monkeypox virus
Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*GP*AP*GP*C)-3')
Chain IDs:G
Chain Length:4
Number of Molecules:1
Biological Source:Monkeypox virus
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (5'-D(P*TP*TP*TP*TP*TP*TP
Chain IDs:C (auth: T)
Chain Length:16
Number of Molecules:1
Biological Source:Monkeypox virus
Ligand Molecules
NA
Primary Citation
Structure and operating principles of a monkeypox virus replisome
Nature ? ? ? (2026)
DOI: 10.1038/s41586-026-10937-2
Primary Citation of related structures
11WZ
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