ISDA: 11WR

Deposition Date 2026-03-16

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

11WR

Keywords:

MEMBRANE PROTEIN

Title:

Cryo-EM structure of Candida albicans fluoride channel FEX in complex with Fab fragment in LiCl

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
HIV-1 M:B_MN (Taxon ID: 11696)
Candida albicans (Taxon ID: 237561)

Expression System(s):

Cricetulus griseus, Saccharomyces cerevisiae

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.56 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:10E8v4 Fab Heavy Chain
Chain IDs:A
Chain Length:232
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:10E8v4 Fab Light Chain
Chain IDs:B
Chain Length:210
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Transmembrane protein gp41,Fl
Chain IDs:C
Chain Length:353
Number of Molecules:1
Biological Source:HIV-1 M:B_MN, Candida albicans

Ligand Molecules

Primary Citation

The structural mechanism of fluoride channel inhibition by lithium in eukaryotes

Kang, C.-Y, Heidari, S, Kolb, S, An, M, Ohi, M.D, Torabifard, H, Stockbridge, R.B.Show

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Primary Citation of related structures

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