ISDA: 11VQ

Deposition Date 2026-03-14

Release Date 2026-09-30

Last Version Date 2026-10-14

Entry Detail

PDB ID:

11VQ

Keywords:

DNA BINDING PROTEIN

Title:

DNA-guided Cas12a

Biological Source:

Source Organism(s):

Acidaminococcus sp. (Taxon ID: 1872103)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.18 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:CRISPR-associated endonucleas
Gene (Uniprot):cas12a
Chain IDs:A
Chain Length:1307
Number of Molecules:1
Biological Source:Acidaminococcus sp.

UniProt ID:U2UMQ6 EC:3.1.21.1,4.6.1.22

Polymer Type:polyribonucleotide
Molecule:Target RNA
Chain IDs:B
Chain Length:38
Number of Molecules:1
Biological Source:Acidaminococcus sp.

Polymer Type:polydeoxyribonucleotide
Molecule:psiDNA
Chain IDs:C
Chain Length:41
Number of Molecules:1
Biological Source:Acidaminococcus sp.

Ligand Molecules

Primary Citation

An intricately folded guide RNA scaffold enables DNA targeting by the compact Cas9d nuclease

Fregoso Ocampo, R, Bravo, J, Das, A, Nielsen, S, Taylor, D.W.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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