ISDA: 11TA

Deposition Date 2026-03-11

Release Date 2026-04-22

Last Version Date 2026-04-22

Entry Detail

PDB ID:

11TA

Keywords:

HYDROLASE

Title:

Cryo-EM structure of substrate engaged p97-Ufd1-NPL4-Faf1 complex (motor focused)

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli 'bl21-gold(de3)plyss ag', Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.58 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Transitional endoplasmic reti
Gene (Uniprot):VCP
Chain IDs:G (auth: A), H (auth: B), I (auth: C), J (auth: D), K (auth: E), L (auth: F)
Chain Length:821
Number of Molecules:6
Biological Source:Homo sapiens

UniProt ID:P55072 Pfam ID:PF02359, PF02933, PF00004, PF17862 EC:3.6.4.6

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Nuclear protein localization
Gene (Uniprot):NPLOC4
Chain IDs:A (auth: G)
Chain Length:611
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q8TAT6 Pfam ID:PF11543, PF05020, PF05021

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin
Gene (Uniprot):UBA52
Chain IDs:B (auth: I), C (auth: K)
Chain Length:76
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P62987 Pfam ID:PF00240

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:FAS-associated factor 1
Gene (Uniprot):FAF1
Chain IDs:D (auth: M), E (auth: O)
Chain Length:173
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q9UNN5 Pfam ID:PF00789

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Ubiquitin recognition factor
Gene (Uniprot):UFD1
Chain IDs:F (auth: P)
Chain Length:313
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q92890 Pfam ID:PF03152, PF24842

Ligand Molecules