ISDA: 11SR

Deposition Date 2026-03-11

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

11SR

Keywords:

MEMBRANE PROTEIN

Title:

EcMscM lacking the first periplasmic helical bundle and the cytoplasmic extension of TM7 in NaCl in a closed conformation

Biological Source:

Source Organism(s):

Escherichia coli K-12 (Taxon ID: 83333)

Expression System(s):

Komagataella pastoris

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

5.10 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Miniconductance mechanosensit
Gene (Uniprot):mscM
Chain IDs:A, B, C, D, E, F, G
Chain Length:873
Number of Molecules:7
Biological Source:Escherichia coli K-12

UniProt ID:P39285 Pfam ID:PF12794, PF21088, PF00924, PF21082

Ligand Molecules

Primary Citation

The bacterial mechanosensitive channel MscM gates through concerted changes in its transmembrane and cytoplasmic domains.

Hiotis, G, Walz, T.Show

Nat Commun ? ? ? (2026)

PMID: 42481478 DOI: 10.1038/s41467-026-75798-9

Primary Citation of related structures

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