11RL image
Deposition Date 2026-03-10
Release Date 2026-09-30
Last Version Date 2026-09-30
Entry Detail
PDB ID:
11RL
Keywords:
REPLICATION
Title:
CryoEM structure of the human origin recognition complex with DNA and CDC6 protein
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
DNA molecule (Taxon ID: 2853804)
Expression System(s):
Spodoptera frugiperda, Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
2.80 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
11RL validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Origin recognition complex su
Gene (Uniprot):ORC1
Chain IDs:E (auth: A)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13415 Pfam ID:PF01426, PF00004, PF17872, PF09079 EC:3.6.4.B8
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Origin recognition complex su
Gene (Uniprot):ORC2
Chain IDs:A (auth: B)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13416 Pfam ID:PF04084, PF24882 EC:3.6.4.B8
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Origin recognition complex su
Gene (Uniprot):ORC3
Chain IDs:F (auth: C)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q9UBD5 Pfam ID:PF07034, PF19675, PF18137 EC:3.6.4.B8
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Origin recognition complex su
Gene (Uniprot):ORC4
Chain IDs:B (auth: D)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O43929 Pfam ID:PF13191, PF14629 EC:3.6.4.B8
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Origin recognition complex su
Gene (Uniprot):ORC5
Chain IDs:G (auth: E)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:O43913 Pfam ID:PF13191, PF21639, PF14630 EC:3.6.4.B8
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Cell division control protein
Gene (Uniprot):CDC6
Chain IDs:H (auth: G)
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q99741 Pfam ID:PF13191, PF22606, PF09079
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (29-MER)
Chain IDs:C (auth: H)
Chain Length:0
Number of Molecules:1
Biological Source:DNA molecule
Polymer Type:polydeoxyribonucleotide
Molecule:DNA (29-MER)
Chain IDs:D (auth: I)
Chain Length:0
Number of Molecules:1
Biological Source:DNA molecule
Ligand Molecules
ATP
MG
Primary Citation
Evolution of Origin Sequence and Recognition for Licensing of Eukaryotic DNA Replication
To Be Published ? ? ? (?)
Primary Citation of related structures
11RL
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