11ON image
Deposition Date 2026-03-06
Release Date 2026-10-14
Last Version Date 2026-10-21
Entry Detail
PDB ID:
11ON
Keywords:
VIRAL PROTEIN
Title:
Divergent interfaces and convergent outcome in the structural basis of HIV-2 Vif antagonism of APOBEC3H
Biological Source:
Source Organism(s):
Pan troglodytes (Taxon ID: 9598)
Homo sapiens (Taxon ID: 9606)
Human immunodeficiency virus 2 (Taxon ID: 11709)
Escherichia coli BL21(DE3) (Taxon ID: 469008)
Expression System(s):
Escherichia coli bl21(de3)
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.10 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
11ON validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:single-stranded DNA cytosine
Gene (Uniprot):APOBEC3H
Chain IDs:A, C (auth: B)
Chain Length:185
Number of Molecules:2
Biological Source:Pan troglodytes
UniProt ID:B7T0U6 EC:3.5.4.38
Polymer Type:polyribonucleotide
Molecule:RNA
Chain IDs:G (auth: C)
Chain Length:10
Number of Molecules:1
Biological Source:Escherichia coli BL21(DE3)
Polymer Type:polyribonucleotide
Molecule:RNA
Chain IDs:H (auth: D)
Chain Length:10
Number of Molecules:1
Biological Source:Escherichia coli BL21(DE3)
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Elongin-B
Gene (Uniprot):ELOB
Chain IDs:E (auth: m)
Chain Length:102
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15370
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Elongin-C
Gene (Uniprot):ELOC
Chain IDs:F (auth: n)
Chain Length:96
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q15369
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Core-binding factor subunit b
Gene (Uniprot):CBFB
Chain IDs:B (auth: o)
Chain Length:170
Number of Molecules:1
Biological Source:Homo sapiens
UniProt ID:Q13951
Structures with similar UniProt ID
Structural Superimposition Protein Blast
Polymer Type:polypeptide(L)
Molecule:Virion infectivity factor
Chain IDs:D (auth: p)
Chain Length:216
Number of Molecules:1
Biological Source:Human immunodeficiency virus 2
UniProt ID:A0A173DUN4
Ligand Molecules
ZN
Primary Citation
Divergent interfaces and convergent outcome in the structural basis of HIV-2 Vif antagonism of APOBEC3H
Nat Commun ? ? ? (2026)
DOI: 10.1038/s41467-026-78197-2
Primary Citation of related structures
11ON
Feedback Form
Name
Email
Institute
Feedback