ISDA: 11NS

Deposition Date 2026-03-05

Release Date 2026-08-05

Last Version Date 2026-08-05

Entry Detail

PDB ID:

11NS

Keywords:

HYDROLASE

Title:

Crystal Structure of viral OTU domain protease from Pacific coast tick nairovirus

Biological Source:

Source Organism(s):

Orthonairovirus dermacentoris (Taxon ID: 3052513)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

1.58 Å

R-Value Free:

0.19

R-Value Work:

0.17

R-Value Observed:

0.17

Space Group:

P 41

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:RNA-directed RNA polymerase L
Chain IDs:A, B
Chain Length:196
Number of Molecules:2
Biological Source:Orthonairovirus dermacentoris

UniProt ID:A0A2R2WU07 EC:2.7.7.48

Ligand Molecules

ACT

SO4

Primary Citation

Insights into the Structure and Function of the OTU Protease Virulence Factors from Emerging Human Nairoviruses.

Gonzalez, D.S, Jalf, A, Moresco, V, Garcia, J, Jaroszewski, L, Matta, D, Nguyen, J, Torres, B, Bergeron, E, Godzik, A, Pegan, S.D.Show

Acs Infect Dis. ? ? ? (2026)

PMID: 42439547 DOI: 10.1021/acsinfecdis.6c00320

Primary Citation of related structures

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