ISDA: 11LR

Deposition Date 2026-03-03

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

11LR

Keywords:

VIRAL PROTEIN

Title:

Human monoclonal antibody 8C5 in complex with rabies virus glycoprotein

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Lyssavirus rabies (Taxon ID: 11292)

Expression System(s):

Drosophila melanogaster, Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.16 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Glycoprotein
Chain IDs:B (auth: A), K (auth: B), L (auth: C)
Chain Length:468
Number of Molecules:3
Biological Source:Lyssavirus rabies

Polymer Type:polypeptide(L)
Molecule:Monoclonal Antibody RVA122 He
Chain IDs:A (auth: E), E (auth: G), F (auth: I)
Chain Length:265
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Monoclonal Antibody RVA122 Li
Chain IDs:C (auth: H), G (auth: D), H (auth: F)
Chain Length:217
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Monoclonal Antibody 8C5 Light
Chain IDs:D (auth: J), I (auth: L), J (auth: N)
Chain Length:216
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Monoclonal Antibody 8C5 Heavy
Chain IDs:M (auth: K), N (auth: M), O (auth: o)
Chain Length:264
Number of Molecules:3
Biological Source:Homo sapiens

Ligand Molecules

NAG

Primary Citation

Antigenic landscape of rabies and related lyssaviruses revealed by cryo-EM

Callaway, H.M, Zyla, D, Hastie, K, Harkins, S, Kothalawalage, S, Samarasinghe, S, Flynn, A, Hariharan, C, Yin, J, Corti, D, Bouhry, H, Dessain, S, Saphire, E.O.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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