11IZ image
Deposition Date 2026-02-26
Release Date 2026-08-26
Last Version Date 2026-09-02
Entry Detail
PDB ID:
11IZ
Keywords:
Title:
Crystal structure of HSC-HSC-AMS bound DesD, the desferrioxamine synthetase from the Streptomyces griseoflavus ferrimycin biosynthetic pathway
Biological Source:
Source Organism(s):
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.47 Å
R-Value Free:
0.21
R-Value Work:
0.17
R-Value Observed:
0.17
Space Group:
C 2 2 21
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:DesD
Chain IDs:A (auth: B), B (auth: A), C (auth: D), D (auth: E), E (auth: C)
Chain Length:612
Number of Molecules:5
Biological Source:Streptomyces griseoflavus
Primary Citation
Modular Inhibitor Approach to Map the Catalytic Trajectory of an Iterative Siderophore Synthetase, DesD.
Acs Bio Med Chem Au 6 393 409 (2026)
PMID: 42630954 DOI: 10.1021/acsbiomedchemau.6c00078
Primary Citation of related structures
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