ISDA: 11IW

Deposition Date 2026-02-26

Release Date 2026-08-19

Last Version Date 2026-08-19

Entry Detail

PDB ID:

11IW

Keywords:

VIRAL PROTEIN/Immune System

Title:

Mouse monoclonal antibody A2 in complex with rabies virus glycoprotein

Biological Source:

Source Organism(s):

Lyssavirus rabies (Taxon ID: 11292)
Homo sapiens (Taxon ID: 9606)
Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens, Drosophila melanogaster

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.01 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Polymer Type:polypeptide(L)
Molecule:Glycoprotein
Chain IDs:A, I (auth: B), J (auth: C)
Chain Length:468
Number of Molecules:3
Biological Source:Lyssavirus rabies

Polymer Type:polypeptide(L)
Molecule:Antibody RVA122 Light Chain
Chain IDs:B (auth: D), G (auth: F), H
Chain Length:217
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Antibody RVA122 Heavy Chain
Chain IDs:D (auth: E), E (auth: I), F (auth: G)
Chain Length:265
Number of Molecules:3
Biological Source:Homo sapiens

Polymer Type:polypeptide(L)
Molecule:Antibody A2 Light Chain
Chain IDs:C (auth: J)
Chain Length:213
Number of Molecules:1
Biological Source:Mus musculus

Polymer Type:polypeptide(L)
Molecule:Antibody A2 Heavy Chain
Chain IDs:K
Chain Length:262
Number of Molecules:1
Biological Source:Mus musculus

Ligand Molecules

Primary Citation

Antigenic landscape of rabies and related lyssaviruses revealed by cryo-EM

Callaway, H.M, Zyla, D, Hastie, K, Harkins, S, Kothalawalage, S, Samarasinghe, S, Flynn, A, Hariharan, C, Yin, J, Corti, D, Bouhry, H, Dessain, S, Saphire, E.O.Show

To Be Published ? ? ? (?)

Primary Citation of related structures

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