11FS image
Deposition Date 2026-02-21
Release Date 2026-08-26
Last Version Date 2026-08-26
Entry Detail
PDB ID:
11FS
Keywords:
RNA BINDING PROTEIN
Title:
Effector complex from type IV-C CRISPR-Cas system
Biological Source:
Source Organism(s):
Pyrococcus abyssi (Taxon ID: 29292)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.20 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
11FS validation report missing
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Cas10IVc
Chain IDs:A
Chain Length:608
Number of Molecules:1
Biological Source:Pyrococcus abyssi
Polymer Type:polypeptide(L)
Molecule:Cas7c
Chain IDs:B (auth: C), G (auth: H), H (auth: I), I (auth: J), J (auth: K), K (auth: L), L (auth: M)
Chain Length:330
Number of Molecules:7
Biological Source:Pyrococcus abyssi
Polymer Type:polypeptide(L)
Molecule:Cas5c
Chain IDs:C (auth: D)
Chain Length:306
Number of Molecules:1
Biological Source:Pyrococcus abyssi
Polymer Type:polydeoxyribonucleotide
Molecule:Non-Target Strand DNA
Chain IDs:D (auth: E)
Chain Length:10
Number of Molecules:1
Biological Source:Pyrococcus abyssi
Polymer Type:polydeoxyribonucleotide
Molecule:Target Strand DNA
Chain IDs:E (auth: F)
Chain Length:47
Number of Molecules:1
Biological Source:Pyrococcus abyssi
Polymer Type:polyribonucleotide
Molecule:crRNA (47-MER)
Chain IDs:F (auth: G)
Chain Length:47
Number of Molecules:1
Biological Source:Pyrococcus abyssi
Polymer Type:polypeptide(L)
Molecule:Cas11c
Chain IDs:M (auth: N), N (auth: O), O (auth: P), P (auth: Q), Q (auth: R), R (auth: S)
Chain Length:124
Number of Molecules:6
Biological Source:Pyrococcus abyssi
Ligand Molecules
MG
ZN
Primary Citation
Type IV-C CRISPR-Cas effector complex recognizes double-stranded DNA and switches on collateral cleavage of ssDNA and RNA
To Be Published ? ? ? (?)
Primary Citation of related structures
11FS
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