ISDA: 11AF

Deposition Date 2026-02-13

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

11AF

Keywords:

TRANSCRIPTION

Title:

Crystal structure of JADE3 PZP domain in complex with Histone H3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.60 Å

R-Value Free:

0.27

R-Value Work:

0.23

R-Value Observed:

0.23

Space Group:

P 2 21 21

Download Validation Report

Macromolecular Entities

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3.1,Protein Jade-3
Gene (Uniprot):H3C1, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3C10, H3C11, H3C12, JADE3
Chain IDs:A, B
Chain Length:190
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P68431,Q92613 Pfam ID:PF00628, PF13832

Ligand Molecules

Primary Citation

Distinct roles of the JADE and BRPF scaffolding subunits of the acetyltransferase HBO1 complex.

Gaurav, N, Ebert, L.K, Lachance, C, Selvam, K, Chen, R.W, Qin, W, Pozharskaia, V, Chi, C, Cote, V, Cox, K.L, Fuchs, H.A, Musselman, C.A, Leonhardt, H, Morral, N, Song, K, Poirier, M.G, Cote, J, Schermer, B, Kutateladze, T.G.Show

Nat Commun ? ? ? (2026)

PMID: 42431943 DOI: 10.1038/s41467-026-75379-w

Primary Citation of related structures

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