11AD image
Deposition Date 2026-02-13
Release Date 2026-04-29
Last Version Date 2026-04-29
Entry Detail
PDB ID:
11AD
Keywords:
Title:
Structural basis for high-affinity inhibitor binding to lipid kinases PIP4K2A and PIP4K2B
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
2.79 Å
R-Value Free:
0.23
R-Value Work:
0.16
R-Value Observed:
0.17
Space Group:
P 61 2 2
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Phosphatidylinositol 5-phosph
Gene (Uniprot):PIP4K2A
Chain IDs:A
Chain Length:377
Number of Molecules:1
Biological Source:Homo sapiens
Primary Citation
PIP4K2A/2B inhibitor suppresses tumor growth in a xenograft model of NSCLC
To Be Published ? ? ? (?)
Primary Citation of related structures
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