10YN image
Deposition Date 2026-02-12
Release Date 2026-05-20
Last Version Date 2026-05-20
Entry Detail
PDB ID:
10YN
Keywords:
TRANSFERASE
Title:
Joint X-ray/neutron structure of E53Q mutant of Thermus thermophilus serine hydroxymethyltransferase (TthSHMT)
Biological Source:
Source Organism(s):
Thermus thermophilus (Taxon ID: 274)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION, NEUTRON DIFFRACTION
R-Value Free:
['0.26
R-Value Work:
['0.23
R-Value Observed:
['?', '?'].00
Space Group:
P 1 21 1
10YN validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Serine hydroxymethyltransfera
Gene (Uniprot):glyA
Mutagens:E53Q
Chain IDs:A, B
Chain Length:405
Number of Molecules:2
Biological Source:Thermus thermophilus
UniProt ID:A0AAD1KUU5 EC:2.1.2.1
Modified Residue
Compound ID Chain ID Parent Comp ID Details 2D Image
LLP A LYS modified residue
Ligand Molecules
DOD
SO4
Primary Citation
Mutation of active site glutamate in serine hydroxymethyltransferase allows trapping a reactive intermediate: a combined neutron and X-ray crystallography study
Rsc Adv 16 ? ? (2026)
DOI: 10.1039/D6RA01814A
Primary Citation of related structures
10YN
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