ISDA: 10RK

Deposition Date 2026-02-03

Release Date 2026-06-10

Last Version Date 2026-06-10

Entry Detail

PDB ID:

10RK

Keywords:

SIGNALING PROTEIN

Title:

Heparin-induced trans tetrameric complex of VEGF, VEGFR2 and Neuropilin 1

Biological Source:

Source Organism(s):

Mus musculus (Taxon ID: 10090)

Expression System(s):

Homo sapiens

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.65 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Isoform VEGF-1 of Vascular en
Gene (Uniprot):Vegfa
Chain IDs:C (auth: A), D (auth: B), H (auth: G), I (auth: H)
Chain Length:175
Number of Molecules:4
Biological Source:Mus musculus

UniProt ID:Q00731 Pfam ID:PF00341, PF14554

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Vascular endothelial growth f
Gene (Uniprot):Kdr
Chain IDs:E (auth: C), G (auth: D), J (auth: I), L (auth: J)
Chain Length:754
Number of Molecules:4
Biological Source:Mus musculus

UniProt ID:P35918 Pfam ID:PF22854, PF21339, PF13927, PF07679, PF22971 EC:2.7.10.1

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Neuropilin-1
Gene (Uniprot):Nrp1
Chain IDs:A (auth: E), B (auth: K), F, K (auth: L)
Chain Length:847
Number of Molecules:4
Biological Source:Mus musculus

UniProt ID:P97333 Pfam ID:PF00431, PF00754, PF00629

Ligand Molecules