10RI image
Deposition Date 2026-02-03
Release Date 2026-06-10
Last Version Date 2026-06-10
Entry Detail
PDB ID:
10RI
Keywords:
SIGNALING PROTEIN
Title:
Dimeric complex of VEGF, VEGFR2 and Neuropilin 1
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
ELECTRON MICROSCOPY
Resolution:
3.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
10RI validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Isoform VEGF-1 of Vascular en
Gene (Uniprot):Vegfa
Chain IDs:A, B
Chain Length:175
Number of Molecules:2
Biological Source:Mus musculus
UniProt ID:Q00731 Pfam ID:PF00341, PF14554
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Vascular endothelial growth f
Gene (Uniprot):Kdr
Chain IDs:C, F (auth: D)
Chain Length:754
Number of Molecules:2
Biological Source:Mus musculus
UniProt ID:P35918 Pfam ID:PF22854, PF21339, PF13927, PF07679, PF22971 EC:2.7.10.1
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Neuropilin-1
Gene (Uniprot):Nrp1
Chain IDs:D (auth: E), E (auth: F)
Chain Length:847
Number of Molecules:2
Biological Source:Mus musculus
UniProt ID:P97333 Pfam ID:PF00431, PF00754, PF00629
Ligand Molecules
CA
NAG
Primary Citation
Mechanisms of VEGFR2 activation by VEGF, neuropilin and heparin
To Be Published ? ? ? (?)
Primary Citation of related structures
10RI
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