10RI image
Deposition Date 2026-02-03
Release Date 2026-06-10
Last Version Date 2026-07-29
Entry Detail
PDB ID:
10RI
Title:
Dimeric complex of VEGF, VEGFR2 and Neuropilin 1
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Expression System(s):
Method Details:
Experimental Method:
Resolution:
3.60 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Isoform VEGF-1 of Vascular en
Gene (Uniprot):Vegfa
Chain IDs:A, B
Chain Length:0
Number of Molecules:2
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Vascular endothelial growth f
Gene (Uniprot):Kdr
Chain IDs:C, F (auth: D)
Chain Length:0
Number of Molecules:2
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Neuropilin-1
Gene (Uniprot):Nrp1
Chain IDs:D (auth: E), E (auth: F)
Chain Length:0
Number of Molecules:2
Biological Source:Mus musculus
Primary Citation
Mechanisms of VEGFR2 activation by VEGF, neuropilin, and heparin.
Sci Adv 12 eaeg6323 eaeg6323 (2026)
PMID: 42455955 DOI: 10.1126/sciadv.aeg6323
Primary Citation of related structures
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