10QV image
Deposition Date 2026-02-02
Release Date 2026-07-08
Last Version Date 2026-07-08
Entry Detail
PDB ID:
10QV
Keywords:
FLAVOPROTEIN
Title:
Crystal Structure of NQO1 Complexed with S-Warfarin
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Escherichia coli
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.90 Å
R-Value Free:
0.22
R-Value Work:
0.17
R-Value Observed:
0.18
Space Group:
P 21 21 21
10QV validation report missing
Macromolecular Entities
Structures with similar UniProt ID
Protein Blast
Polymer Type:polypeptide(L)
Molecule:NAD(P)H dehydrogenase [quinon
Gene (Uniprot):NQO1
Chain IDs:A, B, C, D
Chain Length:294
Number of Molecules:4
Biological Source:Homo sapiens
UniProt ID:P15559 Pfam ID:PF02525 EC:1.6.5.2
Ligand Molecules
FAD
SWF
Primary Citation
Structural and Kinetic Analysis of human NQO1: Evidence for Therapeutic Inhibition by Racemic Warfarin.
Arch.Biochem.Biophys. ? 110911 110911 (2026)
PMID: 42362135 DOI: 10.1016/j.abb.2026.110911
Primary Citation of related structures
10QV
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