10OY image
Deposition Date 2026-01-30
Release Date 2026-10-07
Last Version Date 2026-10-21
Entry Detail
PDB ID:
10OY
Title:
TASK-2 at pH 6.5
Biological Source:
Source Organism(s):
Mus musculus (Taxon ID: 10090)
Homo sapiens (Taxon ID: 9606)
Method Details:
Experimental Method:
Resolution:
2.62 Å
Aggregation State:
PARTICLE
Reconstruction Method:
SINGLE PARTICLE
Macromolecular Entities
Polymer Type:polypeptide(L)
Molecule:Potassium channel TASK2
Gene (Uniprot):Kcnk5
Chain IDs:A, B
Chain Length:344
Number of Molecules:2
Biological Source:Mus musculus
Polymer Type:polypeptide(L)
Molecule:Apolipoprotein A-I
Gene (Uniprot):APOA1
Chain IDs:C (auth: D)
Chain Length:210
Number of Molecules:1
Biological Source:Homo sapiens
Primary Citation
Mechanisms of intracellular pH gating and local anesthetic inhibition of the two-pore domain K + channel TASK-2.
Proc.Natl.Acad.Sci.USA 123 e2604873123 e2604873123 (2026)
PMID: 42848420 DOI: 10.1073/pnas.2604873123
Primary Citation of related structures
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