ISDA: 10ND

Deposition Date 2026-01-28

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

10ND

Keywords:

IMMUNE SYSTEM

Title:

Cryo-EM structure of human IL-10RA in complex with VHH E07

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
Lama glama (Taxon ID: 9844)

Expression System(s):

Homo sapiens, Cricetulus griseus

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

2.40 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Interleukin-10 receptor subun
Gene (Uniprot):IL10RA
Chain IDs:A
Chain Length:227
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q13651

Polymer Type:polypeptide(L)
Molecule:VHH antibody E07
Chain IDs:B
Chain Length:132
Number of Molecules:1
Biological Source:Lama glama

Primary Citation

Cryo-EM structure of human IL-10RA in complex with VHH E07

Xu, H.Show

Nature ? ? ? (2026)

DOI: 10.1038/s41586-026-11176-1

Primary Citation of related structures

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