ISDA: 10JI

Deposition Date 2026-01-22

Release Date 2026-09-23

Last Version Date 2026-09-23

Entry Detail

PDB ID:

10JI

Keywords:

HYDROLASE/TRANSFERASE/RNA

Title:

Structure of Human Argonaute2-miR200b RISC bound to 14nt long target in complex with kinase CK1alpha

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.70 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Protein argonaute-2
Gene (Uniprot):AGO2
Chain IDs:A
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:Q9UKV8 Pfam ID:PF16486, PF08699, PF02170, PF16488, PF16487, PF02171 EC:3.1.26.-

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Casein kinase I isoform alpha
Gene (Uniprot):CSNK1A1
Chain IDs:B
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

UniProt ID:P48729 Pfam ID:PF00069 EC:2.7.11.1

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*UP*AP*AP*UP*AP*CP
Chain IDs:C
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Polymer Type:polyribonucleotide
Molecule:RNA (5'-R(P*AP*CP*CP*UP*AP*UP
Chain IDs:D
Chain Length:0
Number of Molecules:1
Biological Source:Homo sapiens

Ligand Molecules

Primary Citation

Structure of Human Argonaute2-miR200b RISC bound to 14nt long target in complex with kinase CK1alpha

Garg, A, Joshua-Tor, L.Show

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Primary Citation of related structures

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