ISDA: 10GN

Deposition Date 2026-01-19

Release Date 2026-07-22

Last Version Date 2026-07-22

Entry Detail

PDB ID:

10GN

Keywords:

DNA BINDING PROTEIN

Title:

Nucleosome containing an 8oxoG at SHL+3

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)
synthetic construct (Taxon ID: 32630)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

ELECTRON MICROSCOPY

Resolution:

3.00 Å

Aggregation State:

PARTICLE

Reconstruction Method:

SINGLE PARTICLE

Download Validation Report

Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H3.2
Gene (Uniprot):H3C15, H3C14, H3C13
Chain IDs:A, E
Chain Length:135
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:Q71DI3 Pfam ID:PF00125

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H4
Gene (Uniprot):H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16
Chain IDs:B, F
Chain Length:102
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P62805 Pfam ID:PF15511

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2A type 1
Gene (Uniprot):H2AC11, H2AC13, H2AC15, H2AC16, H2AC17
Chain IDs:C, G
Chain Length:129
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P0C0S8 Pfam ID:PF00125, PF16211

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:Histone H2B type 1-C/E/F/G/I
Gene (Uniprot):H2BC4, H2BC6, H2BC7, H2BC8, H2BC10
Chain IDs:D, H
Chain Length:125
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P62807 Pfam ID:PF00125

Polymer Type:polydeoxyribonucleotide
Molecule:601 I strand
Chain IDs:I
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct

Polymer Type:polydeoxyribonucleotide
Molecule:601 J strand
Chain IDs:J
Chain Length:147
Number of Molecules:1
Biological Source:synthetic construct

Ligand Molecules

Primary Citation

8oxoG:A Is Structurally Accommodated in the Nucleosome Core Particle, Yet Inaccessible to MUTYH-Initiated DNA Repair

Vito, A.F, Ling, J.A, Ferrara, J.C, Jacques, C.S, Gillet, N, Gonzalez-Aleman, R, Qiu, Y, Hashemian, M, Trasvina-Arenas, C.H, David, S.S, Delaney, S, Bignon, E, Freudenthal, B.D.Show

Biomolecules 16 999 ? (2026)

DOI: 10.3390/biom16070999

Primary Citation of related structures

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