ISDA: 10EW

Deposition Date 2026-01-15

Release Date 2026-10-21

Last Version Date 2026-10-21

Entry Detail

PDB ID:

10EW

Keywords:

HYDROLASE

Title:

Catalytic domain of GH33 sialidase from Ruminococcus lactaris

Biological Source:

Source Organism(s):

[Ruminococcus] lactaris (Taxon ID: 46228)

Expression System(s):

Escherichia coli

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.04 Å

R-Value Free:

0.19

R-Value Work:

0.15

R-Value Observed:

0.15

Space Group:

C 2 2 2

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Macromolecular Entities

Structures with similar UniProt ID

Structural Superimposition Protein Blast

Polymer Type:polypeptide(L)
Molecule:exo-alpha-sialidase
Chain IDs:A
Chain Length:470
Number of Molecules:1
Biological Source:[Ruminococcus] lactaris

UniProt ID:V8BL81 EC:3.2.1.18

Ligand Molecules

GOL

SO4

Primary Citation

Distinct Processing of Human Milk Oligosaccharides by Early Life Human Gut Microbial Sialidases

Maurer, O.L, Chapel, V.S, Sekela, J.J, Talbert, J, Townsend, S, Zemel, B.S, Wu, G.D, Redinbo, M.R.Show

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