ISDA: 10DJ

Deposition Date 2026-01-13

Release Date 2026-03-18

Last Version Date 2026-03-25

Entry Detail

PDB ID:

10DJ

Keywords:

SIGNALING PROTEIN

Title:

Fyn Kinase Domain-Saracatinib Complex Structure

Biological Source:

Source Organism(s):

Homo sapiens (Taxon ID: 9606)

Expression System(s):

Spodoptera frugiperda

Method Details:

Experimental Method:

X-RAY DIFFRACTION

Resolution:

2.22 Å

R-Value Free:

0.26

R-Value Work:

0.24

R-Value Observed:

0.24

Space Group:

P 21 21 2

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Macromolecular Entities

Structures with similar UniProt ID

Protein Blast

Polymer Type:polypeptide(L)
Molecule:Tyrosine-protein kinase Fyn
Gene (Uniprot):FYN
Chain IDs:A, B
Chain Length:282
Number of Molecules:2
Biological Source:Homo sapiens

UniProt ID:P06241 Pfam ID:PF07714 EC:2.7.10.2

Ligand Molecules

H8H

Primary Citation

Fyn-Saracatinib Complex Structure Reveals an Active State-like Conformation.

Ta, H.M, Sankaran, B, Roush, E.D, Ferreon, J.C, Ferreon, A.C.M, Kim, C.Show

Int J Mol Sci 27 ? ? (2026)

PMID: 41683573 DOI: 10.3390/ijms27031143

Primary Citation of related structures

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