10BT image
Deposition Date 2026-01-10
Release Date 2026-06-10
Last Version Date 2026-06-10
Entry Detail
PDB ID:
10BT
Keywords:
IMMUNE SYSTEM
Title:
X-ray Crystal Structure of A High-Affinity Monoclonal Antibody Sequesters Xylazine
Biological Source:
Source Organism(s):
Homo sapiens (Taxon ID: 9606)
Expression System(s):
Homo sapiens
Method Details:
Experimental Method:
X-RAY DIFFRACTION
Resolution:
1.99 Å
R-Value Free:
0.23
R-Value Work:
0.17
R-Value Observed:
0.17
Space Group:
P 1 21 1
10BT validation report missing
Macromolecular Entities
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody Heavy Chain
Chain IDs:A, B, C, D
Chain Length:234
Number of Molecules:4
Biological Source:Homo sapiens
Protein Blast
Polymer Type:polypeptide(L)
Molecule:Antibody Light Chain
Chain IDs:E, F, G, H
Chain Length:215
Number of Molecules:4
Biological Source:Homo sapiens
Ligand Molecules
A1C4R
CL
Primary Citation
Discovery, Structural Characterization, and Preclinical Evaluation of Monoclonal Antibodies against Xylazine Poisoning
Acs Pharmacol Transl Sci ? ? ? (2026)
DOI: 10.1021/acsptsci.6c00117
Primary Citation of related structures
10BT
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