Search Count: 32
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Crystal Structure Of 6-Fluoropyrazolo[1,5-A]Pyridine Derivative Bound To Kit
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.63 Å Release Date: 2026-08-05 Classification: TRANSFERASE Ligands: A1DJF |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2026-08-05
Ligands: A1DJF
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Braf In Complex With N-(4-Methyl-3-(1-Methyl-2-Oxo-2,3-Dihydro-1H-Benzo[D]Imidazol-5-Yl)Phenyl)-3-(Trifluoromethyl)Benzamide.
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.04 Å Release Date: 2019-10-23 Classification: transferase/transferase inhibitor Ligands: K7S |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-10-23
Ligands: K7S
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Braf In Complex With N-(3-(2-(2-Hydroxyethoxy)-6-Morpholinopyridin-4-Yl)-4-Methylphenyl)-2-(Trifluoromethyl)Isonicotinamide (Lxh254)
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.37 Å Release Date: 2019-09-04 Classification: transferase/transferase inhibitor Ligands: K81 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2019-09-04
Ligands: K81
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Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.45 Å Release Date: 2017-09-06 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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Identification Of An Imidazopyridine Scaffold To Generate Potent And Selective Tyk2 Inhibitors That Demonstrate Activity In An In Vivo Psoriasis Model
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.85 Å Release Date: 2017-09-06 Classification: Transferase/Transferase Inhibitor Ligands: 9ZS |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-09-06
Ligands: 9ZS
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Braf In Complex With N-(3-(Tert-Butyl)Phenyl)-4-Methyl-3-(6-Morpholinopyrimidin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.26 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92D |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 92D
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Braf In Complex With Raf709
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2017-06-28 Classification: TRANSFERASE/TRANSFERASE inhibitor Ligands: 92J |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2017-06-28
Ligands: 92J
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Tyk2 (Jh1) In Complex With Adenosine Di-Phosphate
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.03 Å Release Date: 2013-08-14 Classification: HYDROLASE Ligands: ADP, MG |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-08-14
Ligands: ADP, MG
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Jak2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X2
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Tyk2 Kinase (Jh1 Domain) With 2,6-Dichloro-N-(2-Oxo-2,5-Dihydropyridin-4-Yl)Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: SO4, EDO, GOL, 0X2 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: SO4, EDO, GOL, 0X2
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5
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Jak2 Kinase (Jh1 Domain) In Complex With 2,6-Dichloro-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-06-19 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-06-19
Ligands: 0X5
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-{2-[(Cyclopropylcarbonyl)Amino]Pyridin-4-Yl}Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.31 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0X6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0X6
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.40 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XH |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XH
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Tyk2 (Jh1) In Complex With 2,6-Dichloro-4-Cyano-N-[2-({[(1R,2R)-2-Fluorocyclopropyl]Carbonyl}Amino)Pyridin-4-Yl]Benzamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2013-05-29 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 0XP |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-29
Ligands: 0XP
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The Jak1 Kinase Domain In Complex With Inhibitor
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.10 Å Release Date: 2013-05-22 Classification: TRANSFERASE Ligands: C5I, EDO |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: C5I, EDO
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Jak2 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-[(8As)-2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(8Ah)-Yl]Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.50 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexanecarbonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.90 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J5 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J5
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Jak1 Kinase (Jh1 Domain) In Complex With The Inhibitor (Trans-4-{2-[(1R)-1-Hydroxyethyl]Imidazo[4,5-D]Pyrrolo[2,3-B]Pyridin-1(6H)-Yl}Cyclohexyl)Acetonitrile
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.35 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 1J6 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 1J6
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Jak1 Kinase (Jh1 Domain) In Complex With Compound 34
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.93 Å Release Date: 2013-05-22 Classification: TRANSFERASE/TRANSFERASE INHIBITOR Ligands: 15T |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-05-22
Ligands: 15T