Search Count: 6
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Hydroxyethylamine-Based Inhibitors Of Bace1: P1-P3 Macrocyclization Can Improve Potency, Selectivity, And Cell Activity
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.39 Å Release Date: 2013-07-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1QT |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 1QT
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Bace-1 Inhibitor Complex
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.29 Å Release Date: 2013-07-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1QU |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-10
Ligands: 1QU
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine-Macrocyclic Inhibitor 13
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.30 Å Release Date: 2013-07-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 1R8, GOL, SO4 |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-03
Ligands: 1R8, GOL, SO4
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine-Macrocyclic Inhibitor 19
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:1.91 Å Release Date: 2013-07-03 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, 1R6, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2013-07-03
Ligands: IOD, 1R6, GOL
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Crystal Structure Of Bace1 In Complex With Hydroxyethylamine Inhibitor 37
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.00 Å Release Date: 2012-10-10 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: 0K9, GOL |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-10-10
Ligands: 0K9, GOL
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Structure Of Bace-1 (Beta-Secretase) In Complex With (2R)-N-((2S,3R)-1-(Benzo[D][1,3]Dioxol-5-Yl)-3-Hydroxy-4-((S)-6'-Neopentyl-3',4'-Dihydrospiro[Cyclobutane-1,2'-Pyrano[2,3-B]Pyridine]-4'-Ylamino)Butan-2-Yl)-2-Methoxypropanamide
Organism: Homo sapiens
Method: X-RAY DIFFRACTION Resolution:2.50 Å Release Date: 2012-04-18 Classification: HYDROLASE/HYDROLASE INHIBITOR Ligands: IOD, GOL, 0KN |
Organism: Homo sapiens
Method: X-RAY DIFFRACTION
Release Date: 2012-04-18
Ligands: IOD, GOL, 0KN